[See #477 for detailed background]
Objects obj1 and obj2 are substantially different if and only if one of the following holds:
Inexact numbers z1 and z2 are operationally equivalent if and only if for all procedures f that can be defined as a finite composition of the standard numerical operations specified in section 6.2.6, (f z1) and (f z2) either both raise exceptions or yield results that are not substantially different.
The eqv? procedure returns #t if one of the following holds:
[...]
The eqv? procedure returns #f if one of the following holds:
[...]
The novel feature of this definition is the auxiliary predicate substantially different, which is needed to gracefully avoid circularities and the problems associated with NaNs, both of which plagued the R6RS definition.
The circularity problem is addressed by defining substantially different on numbers in terms of = instead of eqv?. The NaN problem (see below) is addressed by making sure that two numbers can only be substantially different from each other if at least one of them is = to itself.
Note that there is considerable freedom in how "substantially different" is defined. As long as it is capable of making the most coarse distinctions between numbers, that's good enough, because it should always be possible to choose a procedure f that amplifies even the finest distinction between any two inexact numbers that are not operationally equivalent.
For example, suppose that in addition to the usual +0.0 and -0.0, an experimental numeric representation was able to distinguish (x/y+0.0) from (x/y-0.0) for any exact rational x/y. It would still be possible to amplify that distinction to an infinite difference by subtracting x/y and then taking the reciprocal.
Note also that there is considerable freedom in the choice of procedures to allow in the construction of f. The main requirements are that they are sufficient to amplify arbitrary fine distinctions into coarse ones that are substantially different, and that the procedures are pure functions, i.e. they must not use eqv? or eq? (directly or indirectly), they must not cause visible side effects, and their return values must depend only on their arguments. It needn't be a comprehensive set.
Even apart from the NaN problem [see #477 for details], my formulation has four notable changes:
In summary, I would conjecture that the only difference in the resulting requirements (comparing with those intended by the R6RS and likely implemented in practice) has to do with change #1 above.